Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663754 | 0.81 | PDE4D (0.59) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 | |
| SCHEMBL15777023 | 0.79 | PDE4D (0.57) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 | |
| SCHEMBL23926008 | 0.79 | PDE4D (0.57) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 | |
| SCHEMBL10858885 | 0.76 | PDE4D (0.63) | PDE4DDYRK1ALMNAL3MBTL1CYP3A4 | |
| SCHEMBL352117 | 0.76 | PDE4D (0.53) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 | |
| SCHEMBL8006591 | 0.76 | PDE4D (0.53) | PDE4DDYRK1ALMNAL3MBTL1CYP1A2 | |
| SCHEMBL22678620 | 0.74 | PDE4D (0.39) | PDE4DLMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL12106580 | 0.74 | CYP1A2 (0.39) | PDE4DL3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL12106575 | 0.74 | PDE4D (0.43) | PDE4DLMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL10839267 | 0.74 | PDE4D (0.56) | PDE4DDYRK1ALMNAL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104644-A1 | Compositions and Methods for Treating or Preventing Ophthalmic Disease | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-04-29 | — | — | US | claimed |
| US-20090291919-A1 | Compositions and Methods for Treating or Preventing Ophthalmic Light Toxicity | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-11-26 | — | — | US | claimed |
| US-20090286808-A1 | Opsin Stabilizing Compounds and Methods of Use | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-11-19 | — | — | US | claimed |
| EP-2069390-A2 | OPSIN STABILIZING COMPOUNDS AND METHODS OF USE | University of Florida Research Foundation, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013986-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OPHTHALMIC LIGHT TOXICITY | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008013983-A2 | OPSIN STABILIZING COMPOUNDS AND METHODS OF USE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-4321395-A | Preparation of acetanilides | BASF AKTIENGESELLSCHAFT (DE) | 1982-03-23 | — | — | US | claimed |
| US-20230065629-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | disclosed |
| US-11208400-B2 | Substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine derivatives and uses thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-28 | — | — | US | disclosed |
| EP-3526212-B1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AG (DE) | 2021-12-22 | — | — | EP | disclosed |
| WO-2021046179-A1 | NOVEL COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| US-20200055842-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2020-02-20 | — | — | US | disclosed |
| US-8962551-B2 | Quinoxalinyl derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| EP-0007588-B1 | TETRAHYDRO-1,3-OXAZINES, HERBICIDAL COMPOSITIONS CONTAINING ACETANILIDES AS HERBICIDAL AGENTS AND SAID TETRAHYDRO-1,3-OXAZINES AS ANTAGONISTIC AGENTS, AND THEIR USE FOR COMBATING UNDESIRED PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4249935-A | Herbicidal agents | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0009091-A1 | Process for selectively combating undesired plant growth with herbicidal agents comprising acetanilides and N-dichloroacetyl-2,2-dimethyl-1,3-oxazolidine | BASF Aktiengesellschaft (DE) | 1980-04-02 | — | — | EP | disclosed |
| EP-0008649-A1 | Herbicidal agents comprising acetanilides and N-isopropyl-N-propargyl-dichloracetamide and process for selectively combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1980-03-19 | — | — | EP | disclosed |
| EP-0007575-A1 | Herbicidal compositions based on acetanilides and their use in combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |
| EP-0007588-A1 | Tetrahydro-1,3-oxazines, herbicidal compositions containing acetanilides as herbicidal agents and said tetrahydro-1,3-oxazines as antagonistic agents, and their use for combating undesired plant growth | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291919-A1 | Compositions and Methods for Treating or Preventing Ophthalmic Light Toxicity | ALDH1A2, EYA3, PDE6C | PDE4D 490/4885DYRK1A 4837/4885LMNA 1092/4885 |
| US-11208400-B2 | Substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine derivatives and uses thereof | REN, ATP6V1B1, GLS | PDE4D 725/4885DYRK1A 4572/4885LMNA 206/4885 |
| US-20100104644-A1 | Compositions and Methods for Treating or Preventing Ophthalmic Disease | ALDH1A2, PDE6C, EYA3 | PDE4D 320/4885DYRK1A 4850/4885LMNA 979/4885 |
| US-20090286808-A1 | Opsin Stabilizing Compounds and Methods of Use | CRYZ, NR2E3, CRYAB | PDE4D 1075/4885DYRK1A 4495/4885LMNA 1096/4885 |
| US-20200055842-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | REN, ATP6V1B1, GLS | PDE4D 725/4885DYRK1A 4572/4885LMNA 206/4885 |
| US-20230065629-A1 | SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | REN, ATP6V1B1, GLS | PDE4D 725/4885DYRK1A 4572/4885LMNA 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.