Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.33 |
| ▸ | ITGAL | P20701 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966632 | 0.90 | TDP1 (0.36) | ENPP2KMT2AMEN1P2RX3 | |
| SCHEMBL6969844 | 0.88 | FAAH (0.36) | FAAHALOX5APITGB2ICAM1ITGAL | |
| SCHEMBL6965855 | 0.86 | ENPP2 (0.33) | ENPP2P2RX3 | |
| SCHEMBL6973878 | 0.85 | MEN1 (0.35) | ENPP2KMT2AMEN1P2RX3 | |
| SCHEMBL6956997 | 0.82 | FAAH (0.36) | FAAHALOX5APITGB2ICAM1ITGAL | |
| SCHEMBL6966431 | 0.82 | TP53 (0.37) | FAAHALOX5AP | |
| SCHEMBL6960043 | 0.82 | FAAH (0.35) | FAAHALOX5APITGB2ICAM1ITGAL | |
| SCHEMBL6964352 | 0.81 | — | — | |
| SCHEMBL6972940 | 0.81 | FAAH (0.35) | FAAHALOX5APITGB2ICAM1ITGAL | |
| SCHEMBL7083375 | 0.80 | FAAH (0.34) | FAAHALOX5APITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | claimed |
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |