Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971039 | 0.92 | MEN1 (0.43) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6970345 | 0.90 | ALDH1A1 (0.44) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6962441 | 0.85 | KMT2A (0.49) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6964272 | 0.85 | KMT2A (0.49) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6972709 | 0.83 | NPC1 (0.52) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9034160 | 0.82 | MAOB (0.40) | NPC1ALDH1A1L3MBTL1DAO | |
| SCHEMBL224352 | 0.81 | DAO (0.41) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL6971280 | 0.81 | L3MBTL1 (0.44) | MAPTPOLBALDH1A1GAAL3MBTL1 | |
| SCHEMBL6958769 | 0.79 | POLB (0.45) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9079880 | 0.78 | HCAR2 (0.40) | ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |