Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972584 | 0.92 | L3MBTL1 (0.43) | L3MBTL1TSHRPOLBYWHAGMAPT | |
| SCHEMBL6970345 | 0.90 | ALDH1A1 (0.44) | L3MBTL1TSHRPOLBMAPTALDH1A1 | |
| SCHEMBL6966686 | 0.85 | ESR1 (0.43) | L3MBTL1MAPTHRH4HRH3DAO | |
| SCHEMBL6973329 | 0.85 | ESR1 (0.43) | L3MBTL1MAPTHRH4HRH3DAO | |
| SCHEMBL9024167 | 0.84 | YWHAG (0.41) | L3MBTL1TSHRPOLBYWHAGMAPT | |
| SCHEMBL6966124 | 0.83 | ROCK2 (0.47) | L3MBTL1POLBMAPTHRH4HRH3 | |
| SCHEMBL224352 | 0.81 | DAO (0.41) | L3MBTL1TSHRALDH1A1DAOLMNA | |
| SCHEMBL6972511 | 0.81 | ALOX5 (0.45) | L3MBTL1TSHRYWHAGMAPTALDH1A1 | |
| SCHEMBL6972503 | 0.81 | MEN1 (0.43) | L3MBTL1POLBMAPTALDH1A1DAO | |
| SCHEMBL6958769 | 0.79 | POLB (0.45) | L3MBTL1TSHRPOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |