Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 16/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.77 |
| ▸ | HTR1A | P08908 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403830 | 1.00 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL7819881 | 1.00 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL3705476 | 0.98 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL3702815 | 0.94 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Oxalic Acid SCHEMBL3696222 | 0.92 | MPO (0.85) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Oxalic Acid SCHEMBL3698072 | 0.92 | MPO (0.85) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Oxalic Acid SCHEMBL3699113 | 0.90 | MPO (0.84) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL28364393 | 0.87 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL387663 | 0.87 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL30155707 | 0.87 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | UNIVERSITE LIBRE DE BEUXELLES (BE) | 2012-05-17 | — | — | US | disclosed |
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | UNIVERSITE LIBRE DE BEUXELLES (BE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | MPO, SERPINB1, MAOA | MPO 1/4885HTR2A 145/4885TRPM8 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.