Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 11/20 | 1.00 |
| ▸ | HTR2A | P28223 | 6/20 | 1.00 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.97 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.73 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 2/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.66 |
| ▸ | HTR3B | O95264 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | HTR1B | P28222 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR1E | P28566 | 1/20 | 0.66 |
| ▸ | HTR1F | P30939 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364393 | 1.00 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL30155707 | 1.00 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Hydrochloric Acid SCHEMBL1967285 | 0.98 | HTR1A (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Hydrochloric Acid SCHEMBL30487836 | 0.98 | HTR1A (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Methane SCHEMBL7805062 | 0.98 | MPO (0.97) | MPOHTR2ATRPM8HTR1AKMT2A | |
| Cyanide SCHEMBL28693179 | 0.95 | MPO (0.91) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL3702815 | 0.90 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL3705476 | 0.89 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL2537905 | 0.87 | MPO (0.77) | MPOHTR2ATRPM8HTR1AKMT2A | |
| SCHEMBL2403830 | 0.87 | MPO (1.00) | MPOHTR2ATRPM8HTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | claimed |
| CN-115850269-A | Tetrahydro-beta-carboline compound and preparation method and application thereof | 南京工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-112010838-A | Naphthalimide-indole derivative-based intracellular reticulum fluorescent probe and application thereof | 中国科学院化学研究所 | 2020-12-01 | — | — | CN | claimed |
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | UNIVERSITE LIBRE DE BEUXELLES (BE) | 2012-05-17 | — | — | US | claimed |
| WO-2010136546-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | Université Libre de Bruxelles (BE) | 2010-12-02 | — | — | WO | claimed |
| EP-1568770-A2 | Pharmaceutical use of compounds which bind to a mammalian \"trace amine\" receptor | Oregon Health & Science University (US) | 2005-08-31 | — | — | EP | claimed |
| US-20040072187-A1 | Novel mammalian receptor genes and uses | OREGON HEALTH & SCIENCE UNIVERSITY | 2004-04-15 | — | — | US | claimed |
| EP-1319070-A2 | MAMMALIAN RECEPTOR GENES AND USES | Oregon Health & Science University (US) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022801-A2 | MAMMALIAN RECEPTOR GENES AND USES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2002-03-21 | — | — | WO | claimed |
| US-3930948-A | ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES | AJINOMOTO CO., INC. (JA) | 1976-01-06 | — | — | US | claimed |
| WO-2025264058-A9 | NOVEL COMPOUND AND USE THEREOF | 주식회사 진큐어 | 2026-02-26 | — | — | WO | disclosed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| US-20250326719-A1 | FUSED BICYCLIC ALKYLENE LINKED IMIDODICARBONIMIDIC DIAMIDES, METHODS FOR SYNTHESIS, AND USES IN THERAPY | NOVATARG INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250276066-A1 | METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | GERO PTE LTD (SG) | 2025-09-04 | — | — | US | disclosed |
| US-12371404-B2 | Fused bicyclic alkylene linked imidodicarbonimidic diamides, methods for synthesis, and uses in therapy | NOVATARG, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-4806551-A | PLATELET AGGREGATION-INHIBITOR AND THROMBOXAN A2-ANTAGONIST | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0242767-A2 | N-dihydroindolyl ethyl-sulfon amides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| EP-0187122-A2 | 1,3,4-Trisubstituted azacycloalkanes or azacycloalkenes | CIBA-GEIGY AG (CH) | 1986-07-09 | — | — | EP | disclosed |
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |
| US-4146643-A | HALO-, HYDROXY-, ALKYL-, AND ALKOXY-VINCAMINE DERIVATIVES | SANDOZ LTD. (CH) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326719-A1 | FUSED BICYCLIC ALKYLENE LINKED IMIDODICARBONIMIDIC DIAMIDES, METHODS FOR SYNTHESIS, AND USES IN THERAPY | SLC16A7, SLC16A1, HADHB | MPO 3308/4885HTR2A 3926/4885TRPM8 647/4885 |
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | MPO, SERPINB1, MAOA | MPO 1/4885HTR2A 145/4885TRPM8 3657/4885 |
| US-12371404-B2 | Fused bicyclic alkylene linked imidodicarbonimidic diamides, methods for synthesis, and uses in therapy | SLC16A7, SLC16A1, HADHB | MPO 3308/4885HTR2A 3926/4885TRPM8 647/4885 |
| US-20250276066-A1 | METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | UPF1, NLN, BRCA1 | MPO 4842/4885HTR2A 3360/4885TRPM8 3561/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | MPO 4073/4885HTR2A 2339/4885TRPM8 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.