Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984634 | 0.90 | ITGB3 (0.46) | ITGB3ITGA2BF7POLBKMT2A | |
| SCHEMBL6981209 | 0.84 | F7 (0.39) | ITGB3ITGA2BF7TMPRSS15F2 | |
| SCHEMBL6982666 | 0.78 | ADORA2A (0.41) | ITGB3ITGA2BF7PKMTMPRSS15 | |
| SCHEMBL6980649 | 0.76 | ADORA2A (0.41) | ITGB3ITGA2BF7POLBKMT2A | |
| SCHEMBL9262142 | 0.75 | F7 (0.43) | ITGB3ITGA2BF7PKMKMT2A | |
| SCHEMBL6977286 | 0.74 | ITGB3 (0.53) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL9264604 | 0.73 | F7 (0.41) | F7KMT2AF2HTTF10 | |
| SCHEMBL6978828 | 0.71 | ITGB3 (0.48) | ITGB3ITGA2BF7POLBPKM | |
| SCHEMBL6983606 | 0.70 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL9559169 | 0.70 | ITGB3 (0.54) | ITGB3ITGA2BF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |