Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976581 | 0.84 | ITGB3 (0.48) | F7ITGB3ITGA2BKLK1KLK5 | |
| SCHEMBL6972650 | 0.84 | ITGB3 (0.38) | F7ITGB3ITGA2BF10TMPRSS15 | |
| SCHEMBL6983594 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL6982101 | 0.78 | F7 (0.39) | F7ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL6985761 | 0.76 | BRD4 (0.37) | F7ALDH1A1 | |
| SCHEMBL6984634 | 0.73 | ITGB3 (0.46) | F7ITGB3ITGA2BF10TMPRSS15 | |
| SCHEMBL6978828 | 0.71 | ITGB3 (0.48) | F7ITGB3ITGA2BHTTALDH1A1 | |
| SCHEMBL6983606 | 0.71 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL6983954 | 0.71 | ITGB3 (0.61) | ITGB3ITGA2B | |
| SCHEMBL9559169 | 0.70 | ITGB3 (0.54) | ITGB3ITGA2BF10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |