Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 10/20 | 0.39 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983967 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BCYP24A1KDM4E | |
| SCHEMBL6981952 | 0.73 | ALDH1A1 (0.49) | ITGB3ITGA2BKDM4E | |
| SCHEMBL6984397 | 0.72 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL6983016 | 0.71 | ITGB3 (0.47) | ITGB3ITGA2BKDM4E | |
| SCHEMBL6981209 | 0.71 | F7 (0.39) | ITGB3ITGA2B | |
| SCHEMBL6972650 | 0.70 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9258794 | 0.69 | F2 (0.44) | KDM4E | |
| SCHEMBL9558964 | 0.68 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL6985725 | 0.68 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL9426106 | 0.67 | ITGB3 (0.48) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |