Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972650 | 0.90 | ITGB3 (0.38) | ITGB3ITGA2BF7KMT2AMEN1 | |
| SCHEMBL6982666 | 0.81 | ADORA2A (0.41) | ITGB3ITGA2BF7TMPRSS15F2 | |
| SCHEMBL6980649 | 0.79 | ADORA2A (0.41) | ITGB3ITGA2BF7KMT2AF2 | |
| SCHEMBL6978828 | 0.79 | ITGB3 (0.48) | ITGB3ITGA2BF7KMT2AHTT | |
| SCHEMBL9262142 | 0.78 | F7 (0.43) | ITGB3ITGA2BF7KMT2AHTT | |
| SCHEMBL9264604 | 0.76 | F7 (0.41) | F7KMT2AHTTF2F10 | |
| SCHEMBL6977286 | 0.74 | ITGB3 (0.53) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL6981209 | 0.73 | F7 (0.39) | ITGB3ITGA2BF7TMPRSS15HTT | |
| SCHEMBL6976581 | 0.70 | ITGB3 (0.48) | ITGB3ITGA2BF7 | |
| SCHEMBL6978796 | 0.69 | ITGB3 (0.48) | ITGB3ITGA2BF2POLBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |