Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968315 | 0.85 | CYP4F2 (0.45) | MMP1MMP13EPHX2CYP4F2CYP4A11 | |
| SCHEMBL6969747 | 0.81 | MMP13 (0.50) | MMP1MMP13GAA | |
| SCHEMBL6976767 | 0.81 | USP2 (0.45) | MMP1MMP13EPHX2 | |
| SCHEMBL6735747 | 0.81 | CHRNB2 (0.42) | MMP1MMP13EPHX2CYP4F2CYP4A11 | |
| SCHEMBL6727249 | 0.76 | MMP13 (0.41) | MMP1MMP13EPHX2KMT2AGAA | |
| SCHEMBL6972751 | 0.74 | CYP4F2 (0.37) | EPHX2CYP4F2CYP4A11KMT2ANAMPT | |
| SCHEMBL6829624 | 0.73 | CHRNB2 (0.41) | EPHX2CHRNB2CHRNA4 | |
| SCHEMBL6976225 | 0.73 | MMP13 (0.45) | MMP1MMP13 | |
| SCHEMBL6827826 | 0.72 | CYP4F2 (0.43) | MMP1MMP13CYP4F2CYP4A11 | |
| SCHEMBL918530 | 0.72 | CHRNB2 (0.53) | KMT2ANAMPTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053233-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |