Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962591 | 0.80 | HTT (0.71) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL6964138 | 0.79 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL6964190 | 0.78 | BRD4 (0.60) | L3MBTL1SMN1; SMN2LMNAHTTBCHE | |
| SCHEMBL6960672 | 0.72 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL6958783 | 0.70 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL6968459 | 0.69 | BCHE (0.56) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL11195184 | 0.68 | GAA (0.58) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL8675611 | 0.68 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL6971185 | 0.68 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT | |
| SCHEMBL7355012 | 0.66 | BCHE (0.49) | L3MBTL1SMN1; SMN2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |