Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.47 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914150 | 0.85 | HTT (0.59) | MEN1KMT2ASMYD3ALDH1A1LMNA | |
| SCHEMBL6962591 | 0.80 | HTT (0.71) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6972803 | 0.79 | L3MBTL1 (0.69) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6964190 | 0.78 | BRD4 (0.60) | L3MBTL1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL21305748 | 0.77 | NOTUM (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7345134 | 0.76 | MEN1 (0.57) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6972297 | 0.73 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27322991 | 0.73 | PTGDR2 (0.55) | MEN1KMT2AP2RY1 | |
| SCHEMBL8961743 | 0.73 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6967683 | 0.72 | P2RY1 (0.56) | L3MBTL1ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |