Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045656 | 0.83 | RXRA (0.35) | RXRARXRBRXRG | |
| SCHEMBL1924545 | 0.75 | LTB4R2 (0.51) | RAB9APDK1TSPOLTB4R2ALDH1A1 | |
| SCHEMBL7198561 | 0.75 | RXRA (0.44) | RAB9ARXRARXRBRXRGPDK1 | |
| SCHEMBL18396730 | 0.74 | KMT2A (0.41) | RAB9APDK1ALDH1A1NPC1HTT | |
| SCHEMBL1260164 | 0.73 | ACHE (0.53) | RAB9APDK1TSPOALDH1A1NPC1 | |
| SCHEMBL2173392 | 0.72 | PTPRB (0.50) | RAB9APDK1TSPOLTB4R2ALDH1A1 | |
| SCHEMBL12983712 | 0.70 | NR1H2 (0.40) | RXRARXRBRXRGHTTTSHR | |
| SCHEMBL8427222 | 0.68 | ALDH1A1 (0.48) | RAB9APDK1ALDH1A1NPC1HTT | |
| SCHEMBL6827496 | 0.67 | RAB9A (0.53) | RAB9ATSPOLTB4R2ALDH1A1NPC1 | |
| SCHEMBL5238329 | 0.67 | BACE1 (0.35) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149089-B1 | PROCESS TO PREPARE TETRAHYDROTHIOPYRAN-o-FLUORINATED CARBAMATES | UPJOHN CO (US) | 2003-03-26 | — | — | EP | claimed |
| EP-1149089-A2 | PROCESS TO PREPARE CYCLIC-SULFUR FLUORINE CONTAINING OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-31 | — | — | EP | claimed |
| US-6239283-B1 | BACTERICIDES; REACTING 4-ONE-TETRAHYDROTHIOPYRAN | PHARMACIA & UPJOHN COMPANY | 2001-05-29 | — | — | US | claimed |
| WO-2000044741-A2 | PROCESS TO PREPARE CYCLIC-SULFUR FLUORINE CONTAINING OXAZOLIDINONES | PHARMACIA & UPJOHN COMPANY (US) | 2000-08-03 | — | — | WO | claimed |