Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967337 | 0.86 | OPRD1 (0.39) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6969796 | 0.86 | OPRD1 (0.42) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6968627 | 0.86 | ACKR3 (0.40) | ACKR3OPRD1OPRK1OPRL1CCR3 | |
| SCHEMBL6974993 | 0.85 | CCR3 (0.41) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6981032 | 0.85 | OPRD1 (0.38) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6980217 | 0.84 | ACHE (0.43) | OPRD1CCR3 | |
| SCHEMBL6980433 | 0.84 | OPRD1 (0.42) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6969075 | 0.84 | OPRD1 (0.38) | OPRD1OPRK1OPRL1CCR3OPRM1 | |
| SCHEMBL6974842 | 0.84 | OPRD1 (0.39) | OPRD1OPRK1OPRL1OPRM1 | |
| SCHEMBL6973626 | 0.83 | OPRD1 (0.40) | OPRD1OPRK1OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |