Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967337 | 0.91 | OPRD1 (0.39) | ACHEBCHEADRA1AADRA2AADRA2B | |
| SCHEMBL6973626 | 0.89 | OPRD1 (0.40) | GAAADRA1AADRA2AADRA2BADRA2C | |
| SCHEMBL6971228 | 0.88 | ADRA1A (0.44) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6969075 | 0.88 | OPRD1 (0.38) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6969796 | 0.87 | OPRD1 (0.42) | GAAALDH1A1CCR3OPRD1 | |
| SCHEMBL6978058 | 0.87 | ADRA1A (0.46) | ADRA1AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL6980365 | 0.87 | OPRL1 (0.37) | ACHEBCHEADRA1AADRA2AADRA2B | |
| SCHEMBL6981402 | 0.86 | ADRA1A (0.38) | ACHEBCHEGAAADRA1AADRA2A | |
| SCHEMBL6974465 | 0.86 | ALDH1A1 (0.44) | ACHEBCHEGAASMN1; SMN2ADRA1A | |
| SCHEMBL6972305 | 0.86 | FPR3 (0.44) | SMN1; SMN2ALDH1A1KDM4ECNR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |