Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | STAT5B | P51692 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224783 | 0.95 | TDP1 (0.37) | TDP1PTPN1FFAR1ALDH1A1LMNA | |
| SCHEMBL7659011 | 0.82 | PTPN1 (0.36) | TDP1PTPN1ALDH1A1LMNATP53 | |
| SCHEMBL6973854 | 0.81 | CA12 (0.37) | PTPN1PIN1FFAR1ALDH1A1LMNA | |
| SCHEMBL7222557 | 0.79 | ITGB3 (0.38) | — | |
| SCHEMBL7224793 | 0.79 | TDP1 (0.36) | TDP1PTPN1ALDH1A1LMNATP53 | |
| SCHEMBL6978544 | 0.77 | ALDH1A1 (0.52) | TDP1ALDH1A1MAPTADAMTS4 | |
| SCHEMBL7231335 | 0.76 | CASP1 (0.47) | ALDH1A1LMNAHPGDHTTACE | |
| SCHEMBL7230946 | 0.75 | CA12 (0.38) | PTPN1FFAR1ALDH1A1LMNATP53 | |
| SCHEMBL6967103 | 0.74 | CASP1 (0.51) | PIN1FFAR1ALDH1A1 | |
| SCHEMBL7223443 | 0.73 | ALDH1A1 (0.41) | FFAR1ALDH1A1MAPTNPSR1ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |