Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973854 | 0.93 | CA12 (0.37) | CA12CA14CA2CA1CA7 | |
| SCHEMBL7223443 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1FFAR1HIF1A | |
| SCHEMBL7230948 | 0.82 | CA12 (0.37) | CA12CA14CA2CA1CA7 | |
| SCHEMBL7224783 | 0.81 | TDP1 (0.37) | PTPN1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL7228562 | 0.81 | LMNA (0.37) | CA12CA14CA2CA7PTPN1 | |
| SCHEMBL7231335 | 0.80 | CASP1 (0.47) | ALDH1A1HPGDLMNAHTTCTSB | |
| SCHEMBL7231808 | 0.77 | EPHX2 (0.36) | ALDH1A1HPGDLMNANPSR1KDM4E | |
| SCHEMBL6973856 | 0.75 | CA12 (0.37) | CA12CA14CA2CA1CA7 | |
| SCHEMBL6973099 | 0.75 | TDP1 (0.37) | PTPN1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6978544 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586442-B2 | Benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CARNIATO DENIS (FR) | 2003-07-01 | — | — | US | disclosed |
| US-20020187976-A1 | New benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | AVENTIS PHARMA S.A. | 2002-12-12 | — | — | US | disclosed |
| US-6458801-B1 | PHARMACEUTICALLY ACCEPTABLE SALTS AND ITS PRODRUG USEFUL FOR TREATING OSTEOPOROSIS. | AVENTIS PHARMA S.A. (FR) | 2002-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187976-A1 | New benzofurane derivatives, their preparation process, their use as medicaments and the pharmaceutical compositions containing them | CYP2F1, CYP2C19, CYP2B6 | CA12 4808/4885CA14 4561/4885CA2 3768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.