Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974041 | 0.91 | SLC6A3 (0.35) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6979209 | 0.86 | DPP4 (0.43) | DPP4DPP7SLC6A3SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6979873 | 0.76 | MEN1 (0.37) | DPP4DPP7SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6978415 | 0.71 | CNR1 (0.41) | SLC6A3SLC6A2SLC6A4TDP1KDM4E | |
| SCHEMBL6974044 | 0.70 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL6975876 | 0.69 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6977270 | 0.69 | DPP7 (0.32) | DPP4DPP7DPP8 | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.66 | EPHX1 (0.33) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.66 | CYP1A2 (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |