Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969217 | 0.89 | SLC6A2 (0.36) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6982053 | 0.86 | HTR5A (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.84 | CYP1A2 (0.34) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6978462 | 0.83 | MEN1 (0.39) | MEN1KMT2AALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6979209 | 0.81 | DPP4 (0.43) | DPP4DPP7SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6969450 | 0.79 | MEN1 (0.38) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.79 | EPHX1 (0.33) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6973149 | 0.76 | DPP4 (0.36) | DPP4DPP7SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6976764 | 0.74 | MEN1 (0.46) | MEN1KMT2ASLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |