Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979259 | 0.89 | GAA (0.36) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6973149 | 0.86 | DPP4 (0.36) | DPP4DPP7DPP8SLC6A3SLC6A2 | |
| SCHEMBL6970182 | 0.81 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6979873 | 0.81 | MEN1 (0.37) | DPP4DPP7SLC6A3SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6977270 | 0.78 | DPP7 (0.32) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL6974041 | 0.75 | SLC6A3 (0.35) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.71 | ALDH1A1 (0.41) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.71 | EPHX1 (0.33) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6982053 | 0.70 | HTR5A (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.70 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |