Oxalic Acid

Oxalic Acid

SCHEMBL6973522

CC(C)c1nc(CN)n(C)c1Sc1cc(Cl)cc(Cl)c1.O=C(O)C(=O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSP90B1 P14625 5/20 0.31
TRAP1 Q12931 2/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
DRD2 P14416 1/20 0.31
HTR2A P28223 1/20 0.31
HTR7 P34969 1/20 0.31
HTR6 P50406 1/20 0.31
CCR2 P41597 1/20 0.30
CCR5 P51681 1/20 0.30
FABP3 P05413 1/20 0.30
FABP4 P15090 1/20 0.30
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6961212 0.93 HSP90B1 (0.34) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL6960253 0.86 PTGDR2 (0.32) HSP90B1TRAP1HSP90AA1HSP90AB1CCR2
SCHEMBL6969831 0.85 SIRT1 (0.32) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL8345609 0.84 HDAC6 (0.39)
SCHEMBL6972065 0.83 HSP90B1 (0.33) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL6973791 0.83 CYP2C9 (0.33) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL6962129 0.83 HSP90B1 (0.32) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL6163272 0.83 HSP90B1 (0.33) HSP90B1TRAP1HSP90AA1HSP90AB1DRD2
SCHEMBL6961025 0.82 LMNA (0.36) HSP90B1TRAP1HSP90AA1HSP90AB1
SCHEMBL6965470 0.81 SETDB1 (0.33) HSP90B1TRAP1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786455-B1 IMIDAZOLE DERIVATIVE SHIONOGI & CO (JP) 2003-12-03 EP disclosed
US-6147097-A METHOD FOR TREATING AIDS SHIONOGI & CO., LTD. (JP) 2000-11-14 US disclosed
US-5910506-A IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC SHIONOGI & CO., LTD. (JP) 1999-06-08 US disclosed
EP-0786455-A1 IMIDAZOLE DERIVATIVE SHIONOGI & CO., LTD. (JP) 1997-07-30 EP disclosed