Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718547 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL111429 | 0.81 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL13065907 | 0.78 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL359468 | 0.78 | CYP1A2 (0.60) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL11425312 | 0.78 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL28023546 | 0.77 | POLB (0.49) | L3MBTL1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10921299 | 0.77 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL28638612 | 0.77 | TSHR (0.59) | L3MBTL1ALDH1A1MAPTTHRBHPGD | |
| SCHEMBL10624628 | 0.75 | — | — | |
| SCHEMBL351615 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |