Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970884 | 0.81 | CNR2 (0.54) | CNR2ACHECNR1 | |
| SCHEMBL6970142 | 0.79 | CNR2 (0.54) | ALDH1A1CNR2ACHECNR1LMNA | |
| SCHEMBL6973555 | 0.77 | ACHE (0.48) | ALDH1A1CNR2ACHECNR1LMNA | |
| SCHEMBL6973246 | 0.76 | KMT2A (0.47) | ALDH1A1GAACNR2ACHECNR1 | |
| SCHEMBL6975193 | 0.76 | CNR2 (0.51) | ALDH1A1CNR2ACHECNR1LMNA | |
| SCHEMBL6973989 | 0.75 | CNR2 (0.55) | CNR2ACHECNR1MAOB | |
| SCHEMBL6968101 | 0.75 | CNR2 (0.48) | ALDH1A1CNR2ACHECNR1MAPT | |
| SCHEMBL6967341 | 0.73 | MAPT (0.44) | ALDH1A1CNR2ACHECNR1LMNA | |
| SCHEMBL6977942 | 0.73 | CNR2 (0.44) | ALDH1A1GAACNR2ACHECNR1 | |
| SCHEMBL6967696 | 0.73 | ACHE (0.44) | ALDH1A1CNR2ACHECNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |