Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 14/20 | 0.46 |
| ▸ | CNR1 | P21554 | 9/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970884 | 0.80 | CNR2 (0.54) | CNR2CNR1ACHEBCHE | |
| SCHEMBL6971073 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1GAAHPGD | |
| SCHEMBL6973625 | 0.76 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1CNR2CNR1 | |
| SCHEMBL6968493 | 0.76 | HTR6 (0.40) | KMT2AALDH1A1MEN1MAPTEPHA2 | |
| SCHEMBL6970142 | 0.75 | CNR2 (0.54) | KMT2AALDH1A1MEN1CNR2CNR1 | |
| SCHEMBL6966140 | 0.75 | ALDH1A1 (0.50) | KMT2AALDH1A1MEN1GAAHPGD | |
| SCHEMBL6970939 | 0.74 | CNR2 (0.47) | ALDH1A1CNR2CNR1ACHEBCHE | |
| SCHEMBL6973989 | 0.73 | CNR2 (0.55) | CNR2CNR1ACHEBCHE | |
| SCHEMBL6967696 | 0.72 | ACHE (0.44) | KMT2AALDH1A1MEN1CNR2CNR1 | |
| SCHEMBL6977568 | 0.72 | ALDH1A1 (0.49) | KMT2AALDH1A1MEN1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |