Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699131 | 0.86 | KMT2A (0.41) | ALDH1A1HSP90AA1CYP11B1CYP11B2RAB9A | |
| SCHEMBL697334 | 0.86 | RAB9A (0.43) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL697826 | 0.83 | RAB9A (0.41) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL697918 | 0.82 | DRD2 (0.42) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL696367 | 0.81 | OPRD1 (0.51) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL697381 | 0.76 | RAB9A (0.46) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28793808 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5851274 | 0.74 | RAB9A (0.53) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL699209 | 0.73 | RAB9A (0.46) | ALDH1A1HSP90AA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL697396 | 0.73 | RAB9A (0.43) | HSP90AA1CYP11B1CYP11B2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |