Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203164 | 0.84 | GPR139 (0.57) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL5540070 | 0.83 | NAMPT (0.73) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL31019130 | 0.81 | GSK3B (0.60) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL1544890 | 0.81 | GSK3B (0.60) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL6970398 | 0.81 | GSK3B (0.56) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL26926680 | 0.81 | GPR139 (0.55) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL12988864 | 0.81 | L3MBTL1 (0.63) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL3610584 | 0.81 | KAT6A (0.59) | GSK3BALDH1A1GPR139NAMPTGRM5 | |
| SCHEMBL17142140 | 0.80 | HDAC2 (0.64) | ALDH1A1GPR139GAACHRM3VNN1 | |
| SCHEMBL5628377 | 0.80 | NAMPT (0.56) | GSK3BALDH1A1GPR139NAMPTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |