Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576604 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HPGDOPRD1MAPTOPRM1 | |
| SCHEMBL8527824 | 0.78 | HPGD (0.58) | ALDH1A1HPGDLMNAOPRD1MAPT | |
| SCHEMBL22926327 | 0.76 | HPGD (0.59) | ALDH1A1HPGDLMNAMAPTL3MBTL1 | |
| SCHEMBL6892426 | 0.75 | OPRD1 (0.61) | ALDH1A1HPGDOPRD1MAPTOPRM1 | |
| SCHEMBL6794687 | 0.74 | OPRD1 (0.60) | ALDH1A1HPGDLMNAOPRD1MAPT | |
| SCHEMBL29044143 | 0.72 | MEN1 (0.66) | ALDH1A1HPGDLMNAMAPTL3MBTL1 | |
| SCHEMBL4934180 | 0.71 | HPGD (0.50) | ALDH1A1HPGDLMNAOPRD1MAPT | |
| SCHEMBL4678352 | 0.71 | OPRD1 (0.65) | ALDH1A1HPGDLMNAOPRD1MAPT | |
| SCHEMBL6248099 | 0.70 | CYP1A2 (0.51) | ALDH1A1HPGDOPRD1MAPTOPRM1 | |
| SCHEMBL6848182 | 0.70 | ALDH1A1 (0.62) | ALDH1A1HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242402-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | disclosed |