Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | KCNK13 | Q9HB14 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083358 | 0.92 | KCNK13 (0.32) | ENPP2KCNK13 | |
| SCHEMBL6975055 | 0.91 | GRIN1 (0.35) | ENPP2KCNK13GSK3BTLR7 | |
| SCHEMBL7085356 | 0.90 | ENPP2 (0.36) | ENPP2GSK3B | |
| SCHEMBL7082703 | 0.88 | KCNH2 (0.34) | LOXL2GSK3BTLR7 | |
| SCHEMBL6973823 | 0.88 | GRIN1 (0.38) | TLR7 | |
| SCHEMBL6969774 | 0.88 | ENPP2 (0.35) | ENPP2GSK3BTLR7 | |
| SCHEMBL6960983 | 0.87 | ENPP2 (0.32) | ENPP2KCNK13 | |
| SCHEMBL8343038 | 0.86 | TBXA2R (0.42) | ENPP2GSK3B | |
| SCHEMBL7082836 | 0.86 | TLR7 (0.38) | ENPP2LOXL2GSK3BTLR7 | |
| SCHEMBL8494049 | 0.86 | PTGDR2 (0.37) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |