Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800250 | 0.90 | SLC6A9 (0.34) | ALDH1A1LMNAMAPT | |
| SCHEMBL8800652 | 0.87 | NPC1 (0.32) | ALDH1A1 | |
| SCHEMBL6974120 | 0.85 | — | — | |
| SCHEMBL8800346 | 0.85 | MEN1 (0.32) | LMNA | |
| SCHEMBL7084666 | 0.84 | SLC18A3 (0.38) | ALDH1A1MAPT | |
| SCHEMBL6961698 | 0.83 | S1PR3 (0.38) | ALDH1A1LMNA | |
| SCHEMBL7080639 | 0.82 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPT | |
| SCHEMBL8800166 | 0.82 | GRIN1 (0.37) | — | |
| SCHEMBL8802789 | 0.81 | TP53 (0.37) | ALDH1A1LMNAMAPT | |
| SCHEMBL7079379 | 0.80 | MEN1 (0.33) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |