Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957602 | 0.83 | CA12 (0.38) | KMT2APARP1KDM4ENPC1RAB9A | |
| SCHEMBL111544 | 0.81 | KMT2A (0.55) | KMT2APARP1PAK4KDM4EGAA | |
| SCHEMBL697214 | 0.81 | CES2 (0.41) | KMT2APARP1PAK4NPC1RAB9A | |
| SCHEMBL1573195 | 0.81 | NPC1 (0.46) | KMT2APARP1TAAR1NPC1RAB9A | |
| SCHEMBL697784 | 0.80 | MTOR (0.47) | KMT2ATAAR1KDM4EGAANPC1 | |
| SCHEMBL697587 | 0.79 | KMT2A (0.42) | KMT2AKDM4EGAANPC1RAB9A | |
| SCHEMBL696858 | 0.78 | CES2 (0.45) | NPC1RAB9AKCNQ3KCNQ2KCNE1 | |
| SCHEMBL27826895 | 0.78 | LOXL2 (0.44) | KMT2ATAAR1NPC1RAB9A | |
| SCHEMBL697919 | 0.76 | NPC1 (0.44) | KMT2AKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL697433 | 0.76 | NPC1 (0.44) | KMT2AKDM4EGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |