Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697561 | 0.88 | KMT2A (0.44) | KMT2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL702086 | 0.85 | KMT2A (0.46) | KMT2ANPC1RAB9AALDH1A1HPGD | |
| SCHEMBL697121 | 0.81 | TYK2 (0.43) | KMT2ANPC1RAB9AJAK2TYK2 | |
| SCHEMBL11267970 | 0.80 | AKR1C4 (0.41) | KMT2ANPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL697587 | 0.76 | KMT2A (0.42) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL696873 | 0.75 | KMT2A (0.55) | KMT2ANPC1RAB9AALDH1A1JAK2 | |
| SCHEMBL696226 | 0.75 | KMT2A (0.41) | KMT2ANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6087751 | 0.74 | FABP3 (0.48) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11304735 | 0.74 | KMT2A (0.47) | KMT2ANPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL11137294 | 0.73 | NPC1 (0.42) | KMT2ANPC1RAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |