Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984185 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL8311791 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL6978218 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL6978613 | 0.81 | SMN1; SMN2 (0.79) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL6968553 | 0.76 | ACHE (0.64) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL6982324 | 0.76 | ACHE (0.56) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPK1 | |
| SCHEMBL6985089 | 0.75 | KDM4E (0.69) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL8156063 | 0.75 | ACHE (0.56) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPK1 | |
| SCHEMBL6983031 | 0.74 | ACHE (0.64) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL6984467 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2KDM4EALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| US-6121301-A | ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |