Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967255 | 0.94 | AKR1C3 (0.42) | AKR1C3AKR1C2PTGESALOX5HTR6 | |
| SCHEMBL6975974 | 0.91 | AKR1C3 (0.48) | KMT2AMAPTAKR1C3AKR1C2PTGES | |
| SCHEMBL6977877 | 0.89 | HTR6 (0.46) | KMT2AMAPTHTR6MEN1KDM4E | |
| SCHEMBL6965033 | 0.87 | AKR1C3 (0.44) | KMT2AMAPTAKR1C3AKR1C2PTGES | |
| SCHEMBL6968051 | 0.86 | AKR1C3 (0.46) | AKR1C3AKR1C2PTGESALOX5HTR6 | |
| SCHEMBL6977828 | 0.85 | HTR6 (0.44) | MAPTAKR1C3AKR1C2HTR6 | |
| SCHEMBL6975772 | 0.83 | HTR6 (0.43) | MAPTAKR1C3AKR1C2HTR6ALDH1A1 | |
| SCHEMBL6970836 | 0.81 | PKM (0.40) | KMT2AMAPTHTR6ALDH1A1 | |
| SCHEMBL6977822 | 0.81 | MAPT (0.49) | MAPTHTR6ALDH1A1GAA | |
| SCHEMBL6972542 | 0.81 | MAPT (0.47) | KMT2AMAPTAKR1C3AKR1C2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |