Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.45 |
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727248 | 0.84 | MMP13 (0.52) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6727259 | 0.81 | MMP1 (0.43) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6730211 | 0.80 | HDAC3 (0.46) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6969747 | 0.78 | MMP13 (0.50) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6976767 | 0.78 | USP2 (0.45) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6976704 | 0.73 | MMP1 (0.40) | MMP13MMP1 | |
| SCHEMBL6727302 | 0.71 | MMP13 (0.64) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6727303 | 0.71 | MMP13 (0.62) | MMP13MMP1MMP9MMP3MMP2 | |
| SCHEMBL6977761 | 0.69 | HRH3 (0.39) | MMP3HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6735054 | 0.69 | MMP13 (0.52) | MMP13MMP1MMP9MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053233-B1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |