Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976510 | 0.93 | PPARG (0.41) | PPARAPPARGGLO1MAPTLMNA | |
| SCHEMBL6976963 | 0.93 | PPARG (0.41) | PPARAPPARGGLO1MAPTLMNA | |
| SCHEMBL5756031 | 0.86 | ALDH1A1 (0.39) | PPARAPPARGGLO1MAPTLMNA | |
| SCHEMBL5756805 | 0.75 | MAPT (0.46) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5753452 | 0.73 | PPARG (0.51) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5755029 | 0.73 | MMP2 (0.52) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5755465 | 0.73 | PPARG (0.45) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5757695 | 0.72 | POLB (0.51) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5755128 | 0.72 | PPARA (0.52) | PPARAPPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL5754992 | 0.71 | MMP2 (0.49) | PPARAPPARGMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |