Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976963 | 0.88 | PPARG (0.41) | GLO1PPARGPPARAMAPTLMNA | |
| SCHEMBL6976510 | 0.88 | PPARG (0.41) | GLO1PPARGPPARAMAPTLMNA | |
| SCHEMBL6976531 | 0.87 | ALDH1A1 (0.42) | ALDH1A1GLO1MAPTLMNATP53 | |
| SCHEMBL6979299 | 0.86 | CTSD (0.42) | ALDH1A1GLO1MAPTLMNATP53 | |
| SCHEMBL6976460 | 0.86 | PPARA (0.42) | ALDH1A1GLO1PPARGPPARAMAPT | |
| SCHEMBL5756033 | 0.76 | LDHA (0.43) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL5756506 | 0.75 | MMP1 (0.44) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL5756026 | 0.70 | PPARG (0.40) | ALDH1A1PPARGPPARAMAPTLMNA | |
| SCHEMBL6976625 | 0.68 | ALDH1A1 (0.38) | ALDH1A1PPARGPPARAMAPTKMT2A | |
| SCHEMBL10532228 | 0.68 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-B1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |