Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976963 | 0.97 | PPARG (0.41) | PPARGPPARAGLO1MAPTLMNA | |
| SCHEMBL6976460 | 0.93 | PPARA (0.42) | PPARGPPARAGLO1MAPTLMNA | |
| SCHEMBL5756031 | 0.88 | ALDH1A1 (0.39) | PPARGPPARAGLO1MAPTLMNA | |
| SCHEMBL5757446 | 0.76 | LDHA (0.47) | PPARGPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5755128 | 0.74 | PPARA (0.52) | PPARGPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5757436 | 0.74 | MMP2 (0.47) | PPARGPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5753807 | 0.73 | PPARA (0.51) | PPARGPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL6976531 | 0.73 | ALDH1A1 (0.42) | GLO1MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL5754622 | 0.73 | LDHA (0.47) | PPARGPPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5756604 | 0.72 | PPARA (0.48) | PPARGPPARAMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-A4 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2003-01-02 | — | — | EP | disclosed |
| EP-1208092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001077092-A1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-10-18 | — | — | WO | disclosed |