Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976769 | 0.91 | MAOB (0.44) | MAOBDPP4 | |
| SCHEMBL6976617 | 0.90 | SMYD3 (0.42) | RAB9ANPC1SMN1; SMN2TP53LMNA | |
| SCHEMBL6976833 | 0.89 | F2 (0.36) | RAB9ANPC1TP53F2MAOB | |
| SCHEMBL6976541 | 0.88 | MAOB (0.47) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL6972547 | 0.88 | F2 (0.43) | F2MAOB | |
| SCHEMBL6975942 | 0.88 | F2 (0.35) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL6976859 | 0.84 | F2 (0.39) | SMN1; SMN2F2 | |
| SCHEMBL17145025 | 0.81 | NFKB1 (0.41) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL17145027 | 0.81 | NFKB1 (0.41) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL6972814 | 0.79 | DPP4 (0.34) | LMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |