Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978874 | 0.88 | CTSK (0.43) | DPP4PIK3CAPLA2G4A | |
| SCHEMBL8939651 | 0.82 | EPHA2 (0.35) | ACKR3 | |
| SCHEMBL6976473 | 0.79 | RAB9A (0.37) | DPP4LMNA | |
| SCHEMBL6972547 | 0.79 | F2 (0.43) | — | |
| SCHEMBL6970495 | 0.79 | LMNA (0.35) | DPP4PIK3CALMNA | |
| SCHEMBL6976769 | 0.78 | MAOB (0.44) | DPP4 | |
| SCHEMBL6976617 | 0.76 | SMYD3 (0.42) | DPP4PIK3CALMNA | |
| SCHEMBL6976833 | 0.76 | F2 (0.36) | — | |
| SCHEMBL6976541 | 0.75 | MAOB (0.47) | DPP4LMNA | |
| SCHEMBL7509967 | 0.75 | CTSK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |