Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976617 | 0.92 | SMYD3 (0.42) | MAOBDPP4 | |
| SCHEMBL6976473 | 0.91 | RAB9A (0.37) | MAOBDPP4 | |
| SCHEMBL6976833 | 0.91 | F2 (0.36) | MAOBMAPT | |
| SCHEMBL6976541 | 0.90 | MAOB (0.47) | MAOBMAPTDPP4MAOA | |
| SCHEMBL6972547 | 0.90 | F2 (0.43) | MAOB | |
| SCHEMBL6975942 | 0.90 | F2 (0.35) | MAOBMAOA | |
| SCHEMBL8939612 | 0.83 | F2 (0.40) | MAOBMAPTSNCA | |
| SCHEMBL6970495 | 0.79 | LMNA (0.35) | DPP4 | |
| SCHEMBL7498504 | 0.78 | F2 (0.46) | — | |
| SCHEMBL6972814 | 0.78 | DPP4 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |