Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976769 | 0.91 | MAOB (0.44) | MAPTMAOB | |
| SCHEMBL6976617 | 0.90 | SMYD3 (0.42) | TP53MAOBNPC1RAB9A | |
| SCHEMBL6976473 | 0.89 | RAB9A (0.37) | F2TP53MAOBNPC1RAB9A | |
| SCHEMBL6976541 | 0.88 | MAOB (0.47) | MAPTTP53MAOBNPC1RAB9A | |
| SCHEMBL6972547 | 0.88 | F2 (0.43) | F2MAOB | |
| SCHEMBL6975942 | 0.88 | F2 (0.35) | F2TP53MAOBNPC1RAB9A | |
| SCHEMBL7506385 | 0.84 | F2 (0.40) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6970495 | 0.79 | LMNA (0.35) | F2PRSS1 | |
| SCHEMBL8939612 | 0.77 | F2 (0.40) | F2MAPTMAOB | |
| SCHEMBL8939655 | 0.76 | F2 (0.47) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |