Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950412 | 0.84 | MAPT (0.40) | IDO1HPGD | |
| SCHEMBL360584 | 0.78 | MAPT (0.44) | RAPGEF4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3843882 | 0.76 | MAPT (0.42) | IDO1RAPGEF4ALDH1A1 | |
| Bromide SCHEMBL20984180 | 0.76 | MAPT (0.42) | RAPGEF4ALDH1A1 | |
| SCHEMBL14553859 | 0.74 | RAPGEF4 (0.45) | TSHRRAPGEF4ALDH1A1 | |
| SCHEMBL27995398 | 0.74 | TSHR (0.35) | TSHRRAPGEF4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL20856494 | 0.73 | CA1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL1997250 | 0.72 | ALDH1A1 (0.45) | TSHRTP53CYP3A4IDO1RAPGEF4 | |
| Hydrochloric Acid SCHEMBL28391176 | 0.72 | MAP2K2 (0.30) | — | |
| Bromide SCHEMBL20984465 | 0.70 | ALDH1A1 (0.43) | TSHRTP53CYP3A4IDO1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126335-B1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9815792-B2 | Method for producing carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-14 | — | — | US | disclosed |
| EP-3126335-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-08 | — | — | EP | disclosed |
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
| WO-2015150300-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
| WO-2015150300-A1 | N-(1-(HETERO)ARYL-1H-PYRAZOL-4-YL)-(HETERO)ARYLAMIDE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-08 | — | — | WO | disclosed |
| EP-1200428-B1 | SUBSTITUTED BENZOXAZOLES | BASF AG (DE) | 2003-04-16 | — | — | EP | disclosed |
| EP-1200428-A1 | SUBSTITUTED BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001012625-A2 | SUBSTITUTED BENZOXAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022168-A1 | METHOD FOR PRODUCING CARBOXAMIDES | AADAC, CPS1, NAAA | TSHR 3595/4885TP53 4857/4885CYP3A4 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.