Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.37 |
| ▸ | HTR2B | P41595 | 7/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976937 | 1.00 | DPP4 (0.40) | DPP4SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL6980205 | 0.84 | CARM1 (0.43) | DPP4SIGMAR1TMEM97OPRM1 | |
| SCHEMBL6983930 | 0.80 | CHRM2 (0.43) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6981384 | 0.79 | DRD2 (0.43) | SIGMAR1DRD2 | |
| SCHEMBL7811043 | 0.79 | DRD2 (0.43) | SIGMAR1DRD2 | |
| SCHEMBL6981562 | 0.79 | DRD2 (0.43) | SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL6985847 | 0.78 | DRD2 (0.42) | SIGMAR1DRD2 | |
| Bromide SCHEMBL7811682 | 0.78 | DRD2 (0.42) | SIGMAR1DRD2 | |
| Bromide SCHEMBL7811677 | 0.78 | DRD2 (0.42) | SIGMAR1DRD2 | |
| Hydrochloric Acid SCHEMBL6984757 | 0.78 | DRD2 (0.42) | SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |