Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 9/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 9/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985084 | 0.89 | AGTR2 (0.36) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL6979705 | 0.85 | PRMT6 (0.43) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL6976937 | 0.84 | DPP4 (0.40) | SIGMAR1TMEM97OPRM1DPP4 | |
| SCHEMBL6976935 | 0.84 | DPP4 (0.40) | SIGMAR1TMEM97OPRM1DPP4 | |
| SCHEMBL6983930 | 0.83 | CHRM2 (0.43) | SIGMAR1HRH3BCHEOPRM1 | |
| SCHEMBL6976496 | 0.83 | CARM1 (0.42) | CARM1PRMT6 | |
| SCHEMBL7811043 | 0.83 | DRD2 (0.43) | CARM1PRMT6SIGMAR1 | |
| SCHEMBL6981384 | 0.83 | DRD2 (0.43) | CARM1PRMT6SIGMAR1 | |
| SCHEMBL6981562 | 0.83 | DRD2 (0.43) | CARM1PRMT6SIGMAR1 | |
| SCHEMBL6985365 | 0.82 | LMNA (0.42) | SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |