Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979991 | 0.92 | TSHR (0.43) | CNR2TBXAS1PTGDR2KDM4EPIK3CA | |
| SCHEMBL6968571 | 0.85 | GABRA1 (0.43) | TBXAS1ALDH1A1 | |
| SCHEMBL7666493 | 0.82 | GABRA1 (0.40) | CNR2TBXAS1KDM4E | |
| SCHEMBL6981401 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGD | |
| SCHEMBL8144941 | 0.81 | CYP19A1 (0.38) | TBXAS1KDM4EALDH1A1 | |
| SCHEMBL8145307 | 0.78 | PARP1 (0.38) | TBXAS1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL8153648 | 0.77 | VKORC1 (0.40) | CNR2KDM4EALDH1A1 | |
| SCHEMBL7670695 | 0.76 | GABRA5 (0.43) | ALDH1A1 | |
| SCHEMBL6979201 | 0.76 | GABRA1 (0.41) | TBXAS1GAAPTGDR2KDM4EALDH1A1 | |
| SCHEMBL6974694 | 0.76 | PTGDR2 (0.45) | TBXAS1PTGDR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |