Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SPTLC2 | O15270 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974848 | 0.90 | SPTLC2 (0.53) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL6973267 | 0.87 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL6979721 | 0.84 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL6977288 | 0.84 | SPTLC2 (0.55) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL6418776 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL7345953 | 0.78 | HSD11B1 (0.51) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| Hydrochloric Acid SCHEMBL19893016 | 0.77 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DSPTLC2 | |
| SCHEMBL7350151 | 0.77 | AVPR1A (0.65) | ABCB11HTR1ACHRM1AVPR2OXTR | |
| SCHEMBL14532659 | 0.76 | PTGDR2 (0.54) | L3MBTL1SMN1; SMN2MAPTLMNABCHE | |
| SCHEMBL7346875 | 0.75 | AVPR1A (0.58) | ABCB11HTR1ACHRM1AVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1283055-A1 | SOLUBLE BETA AMYLOID PRECURSOR PROTEIN SECRETION PROMOTERS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216398-A1 | Soluble beta amyloid precursor protein secretion promoters | APP, BDNF, BACE1 | PDE4A 2235/4885PDE4B 2563/4885PDE4C 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.