Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRD1 | O95696 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970167 | 0.97 | SMN1; SMN2 (0.51) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| SCHEMBL6977191 | 0.93 | F2 (0.55) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| SCHEMBL6978117 | 0.85 | TSHR (0.43) | F2ALDH1A1PKMPOLBBRPF1 | |
| SCHEMBL6637025 | 0.84 | PAX8 (0.64) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| SCHEMBL8137693 | 0.81 | F2 (0.56) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| SCHEMBL6637137 | 0.80 | GAA (0.44) | SMN1; SMN2PAX8ALDH1A1PKMPOLB | |
| SCHEMBL6635412 | 0.79 | F2 (0.46) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| SCHEMBL6486632 | 0.78 | F2 (0.50) | F2SMN1; SMN2ALDH1A1RAB9AMEN1 | |
| SCHEMBL6634682 | 0.77 | LMNA (0.53) | F2SMN1; SMN2PAX8ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL7244675 | 0.77 | F2 (0.49) | F2SMN1; SMN2ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220845-B1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-08-13 | — | — | EP | disclosed |
| US-6413990-B1 | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |