Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | BRD1 | O95696 | 2/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.50 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978112 | 0.93 | F2 (0.49) | F2PAX8POLBALDH1A1PKM | |
| SCHEMBL6637025 | 0.90 | PAX8 (0.64) | F2PAX8POLBALDH1A1PKM | |
| SCHEMBL6970167 | 0.89 | SMN1; SMN2 (0.51) | F2PAX8POLBALDH1A1PKM | |
| SCHEMBL6486632 | 0.84 | F2 (0.50) | F2ALDH1A1BRD4THRBRAB9A | |
| SCHEMBL6634682 | 0.83 | LMNA (0.53) | F2PAX8POLBALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL7244675 | 0.83 | F2 (0.49) | F2ALDH1A1BRD4THRBRAB9A | |
| SCHEMBL8027058 | 0.82 | F2 (0.70) | F2PAX8POLBALDH1A1PKM | |
| SCHEMBL6977907 | 0.80 | F2 (0.68) | F2PAX8POLBALDH1A1PKM | |
| SCHEMBL6159720 | 0.78 | ITK (0.46) | ALDH1A1BRD4TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6475543 | 0.77 | KDM4E (0.48) | F2LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220845-B1 | ARYL-SULFONAMIDE SUBSTITUTED BENZIMIDAZOL DERIVATIVES AND USE OF SAID AS TRYPTASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-08-13 | — | — | EP | disclosed |
| US-6413990-B1 | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |