Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702086 | 0.85 | KMT2A (0.46) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL697291 | 0.81 | KMT2A (0.46) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL712135 | 0.77 | NPC1 (0.65) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL697617 | 0.76 | NPC1 (0.42) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL697619 | 0.75 | KMT2A (0.41) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL1573195 | 0.75 | NPC1 (0.46) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL697771 | 0.75 | SMPD3 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL696628 | 0.73 | NPC1 (0.47) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL11137294 | 0.73 | NPC1 (0.42) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 | |
| SCHEMBL698900 | 0.73 | KMT2A (0.46) | RAB9ANPC1NISCHKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |